| 1. Discuss if you have any history of substance use disorder or a mental health condition such as schizophrenia. |
2. Discuss if you are taking any prescription medications to treat other conditions, such as pain, depression, cancer, or for an autoimmune disorder. |
3. Report and discuss any concerning effects of medical marijuana with your physician. |
| Patients with these conditions are often excluded from clinical trials that examine the effectiveness and safety of medical marijuana, due to concerns about an increased risk of adverse events. | Certain compounds found in medical marijuana (e.g., cannabidiol) can interact with medications for those conditions and may require further dosing adjustments that should be guided by a physician. | There are many possible interactions between medical marijuana, diseases, medications, and other substances. Therefore, regular communication with your healthcare provider can assist in identifying risks. |
Please note: This document is for informational purposes only, but is not medical or legal advice and should not be used to make healthcare decisions. Please consult your healthcare provider to find out what treatment options are available for you.
1The 2020 Florida Statutes. Title XXIX, Chapter 381, section 381.986: Medical use of marijuana.
2Jugl S et al. A Mapping Literature Review of Medical Cannabis Clinical Outcomes and Quality of Evidence in Approved Conditions in the USA from 2016 to 2019. Med Cannabis Cannabinoids 2021.
3National Academy of Sciences, Engineering, and Medicine. 2017. The health effects of cannabis and cannabinoids: The current state of evidence and recommendations for research. Washington, DC: The National Academies Press.
4Bonn-Miller MO, Sisley S, Riggs P, Yazar-Klosinski B, Wang JB, Loflin MJE, Shechet B, Hennigan C, Matthews R, Emerson A, Doblin R. The short-term impact of 3 smoked cannabis preparations versus placebo on PTSD symptoms: A randomized cross-over clinical trial. PLoS One. 2021 Mar 17;16(3):e0246990.
5Bonn-Miller MO, Brunstetter M, Simonian A, Loflin MJ, Vandrey R, Babson KA, Wortzel H. The Long-Term, Prospective, Therapeutic Impact of Cannabis on Post-Traumatic Stress Disorder. Cannabis Cannabinoid Res. 2022 Apr;7(2):214-223.
6Brown, J.D.; Winterstein, A.G. Potential Adverse Drug Events and Drug–Drug Interactions with Medical and Consumer Cannabidiol (CBD) Use. J. Clin. Med. 2019, 8, 989.
Updated 2024
