Pain that is caused by or originating from many medical conditions, and that lasts 3 months or longer. “Nonmalignant” means that the pain is not associated with cancer.

| 1. Discuss if you are taking any prescription medications for pain. |
2. Discuss if you have mental health conditions, such as depression or anxiety. |
3. Report and discuss any concerning effects of medical marijuana with your physician. |
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Opioids, such as morphine, have increased safety risks when combined with medical marijuana. Other medications used for chronic pain, such as gabapentin, may be unsafe to combine with medical marijuana. |
It is common to experience depressive or anxiety symptoms with a chronic pain condition. Research is not clear on how medical marijuana may affect mental health symptoms when present with another health condition, such as pain. |
There are many possible interactions between medical marijuana, diseases, medications, and other substances. Therefore, regular communication with your healthcare provider can assist in identifying risks. |
Please note: This document is for informational purposes only, but is not medical or legal advice and should not be used to make healthcare decisions. Please consult your healthcare provider to find out what treatment options are available for you.
1The 2020 Florida Statutes. Title XXIX, Chapter 381, section 381.986: Medical use of marijuana.
2Jugl S et al. A Mapping Literature Review of Medical Cannabis Clinical Outcomes and Quality of Evidence in Approved Conditions in the USA from 2016 to 2019. Med Cannabis Cannabinoids 2021.
3National Academy of Sciences, Engineering, and Medicine. 2017. The health effects of cannabis and cannabinoids: The current state of evidence and recommendations for research. Washington, DC: The National Academies Press.
4Systematic Review: Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain. Content last reviewed November 2023. Effective Health Care Program, Agency for Healthcare Research and Quality, Rockville, MD.
Updated 2023