
| 1. Discuss any need for dosing adjustments for HIV/AIDS treatments, or for prescription medications to treat other conditions, such as pain, depression, cancer, or for an autoimmune disorder. |
2. Discuss if you have any history of substance use disorder or mental health conditions such as schizophrenia. |
3. Report and discuss any concerning effects of medical marijuana with your physician. |
| Certain compounds found in medical marijuana (e.g., cannabidiol) can interact with medications for HIV/AIDS and other conditions and may require further dosing adjustments that should be guided by a physician. |
Patients with these conditions are often excluded from clinical trials that examine the effectiveness and safety of medical marijuana, due to concerns about an increased risk of adverse events. | There are many possible interactions between medical marijuana, diseases, medications, and other substances. Therefore, regular communication with your healthcare provider can assist in identifying risks. |
Please note: This document is for informational purposes only, but is not medical or legal advice and should not be used to make healthcare decisions. Please consult your healthcare provider to find out what treatment options are available for you.
1The 2020 Florida Statutes. Title XXIX, Chapter 381, section 381.986: Medical use of marijuana.
2Jugl S et al. A Mapping Literature Review of Medical Cannabis Clinical Outcomes and Quality of Evidence in Approved Conditions in the USA from 2016 to 2019. Med Cannabis Cannabinoids 2021.
3Wood RB. The natural history and clinical features of HIV infection in adults and adolescents. In: UpToDate, Sax PE & Mitty J(Eds.), Wolters Kluwer. (Accessed on April 7, 2024.)
4National Academy of Sciences, Engineering, and Medicine. 2017. The health effects of cannabis and cannabinoids: The current state of evidence and recommendations for research. Washington, DC: The National Academies Press.
5Haney M, Rabkin J, Gunderson E, Foltin RW. Dronabinol and marijuana in HIV(+) marijuana smokers: acute effects on caloric intake and mood. Psychopharmacology (Berl). 2005;181(1):170-178.
6Haney M, Gunderson EW, Rabkin J, et al. Dronabinol and marijuana in HIV-positive marijuana smokers: Caloric intake, mood, and sleep. Journal of Acquired Immune Deficiency Syndromes. 2007;45(5):545-554.
7Abrams DI, Jay CA, Shade SB, et al. Cannabis in painful HIV-associated sensory neuropathy: A randomized placebo-controlled trial. Neurology. 2007;68(7):515-521.
8Ellis RJ, Toperoff W, Vaida F, et al. Smoked medicinal cannabis for neuropathic pain in HIV: a randomized, crossover clinical trial. Neuropsychopharmacology. 2009;34(3):672‐680.
9Brown, J.D.; Winterstein, A.G. Potential Adverse Drug Events and Drug–Drug Interactions with Medical and Consumer Cannabidiol (CBD) Use. J. Clin. Med. 2019, 8, 989. https://doi.org/10.3390/jcm8070989
Updated 2024